Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...
Study design to create a database of transcripts, called TRAILS (TRAnscriptomic resource of Immune cells using Long-read Sequencing), from different human immune cell subsets and downstream analysis.
Viral-infected cell lines are a commonly used experimental system to investigate host mechanisms and restriction factors, which inhibit viral replication and infection. In the present study, ...
Braunschweig, U., Gueroussov, S., Plocik, A. M., Graveley, B. R. and Blencowe, B. J. Dynamic Integration of Splicing within Gene Regulatory Pathways. Cell 152, 1252 ...
What eventually becomes a graduate student’s PhD thesis work is rarely the project they initially pursued. However, in rare cases like with recent PhD graduate Dr. April Lo from Dr. Alice Berger’s Lab ...
Differential gene expression analysis of male C57BL/6 mice exposed to graded levels (10%−40%) of short-term (3 months) CR compared to mice fed a control diet of AL ...
Long-read platforms that can sequence RNA molecules over 10,000 bases in length end-to-end hold great potential for use in characterizing variations in the transcriptome. But while these technologies ...
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