Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, ...

Researchers at Tulane University School of Medicine have discovered that if animal cells gain an extra set of chromosomes, a ...

BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...

A team led by Mount Sinai researchers has identified stem cell populations and mechanisms underlying age-related degeneration in glands that are vital to eye function. The findings, published in ...

A new preclinical study from Weill Cornell Medicine found that the protein caspase-5 (CASP5), long thought to be a foot ...

The research team engineered CD8+ Jurkat T cells to express SVAR16, a human TCR with intermediate-to-high 2D affinity for the SARS-CoV-2-derived epitope HLAA2:01–YLQ, using lentiviral transduction.

Cells long thought to play a secondary role in brain function build their own far-reaching connections, according to a new ...

UNC postdoctoral Ajit Prakash explores how G proteins function as intracellular pH sensors and how this affects cell ...

The simplest explanations are often the most appealing, yet they are also often the most incomplete. For a long time, it ...