Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

A team at Huntsman Cancer Institute at the University of Utah (the U) has uncovered a previously unrecognized molecular ...

New research has identified a protein that could serve as both a biomarker and therapeutic target to weaken stem-like cancer cells responsible for colorectal cancer relapse.

Sapient, a leader in multi-omics data generation for biomarker discovery and clinical insight delivery, has announced the launch of its Tumor Protein Mapping Platform as a suite of mass ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

A hallmark of type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas that produce and release ...

A key molecular dynamic could be the key to fighting tumors while allowing patients to still receive life-saving cell ...

• BTK inhibitors work by targeting and blocking the BTK enzyme, which is crucial for the survival and growth of cancerous B-cells in mantle cell lymphoma (MCL). This cuts off the cancer cell’s support ...