The cerebellum is instrumental in coordinating movement and refining motor control through intricate neuronal circuitry, with Purkinje cells serving as the central integrators of sensory inputs and ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring ...

Single-cell functional analysis enables scientists to examine the unique characteristics of each cell within organs, tissues, and cell cultures. Unlike bulk-cell analysis, single-cell analysis allows ...

Type 2 diabetes (T2D) is a chronic and widely prevalent condition characterized by a progressive loss of glycemic control driven by both insulin resistance and β-cell dysfunction. The disease has long ...

In a new study published in Science titled, “Mitochondrial metabolism and signaling direct dendritic cell function in antitumor immunity,” researchers from St. Jude Children’s Research Hospital have ...

Creating artificial systems that mimic the functioning of cells is one of the goals of what is known as synthetic biology. These models, known as synthetic or biomimetic cells, allow some of the basic ...