Forbes

Fighting Cancer: A Basic Guide To Checkpoint Inhibitors

A woman receiving an IV at the hospital. This article is part of an ongoing series on novel cancer advances, including immunotherapies such as CAR T therapy and checkpoint inhibitors. Future ...
ascopubs.org

Systemic levels of the soluble co-inhibitory immune checkpoints, CTLA-4, LAG-3, PD-1/PD-L1, and TIM-3 are markedly increased in basal cell carcinoma.

Detection of homologous recombination deficiency (HRD) in cell-free DNA (cfDNA) using an amplicon-based next-generation sequencing (NGS) assay. This is an ASCO Meeting Abstract from the 2022 ASCO ...
News Medical

Transcript and protein level immune-checkpoint analysis of glioma

Glioma, a prevailing type of malignant brain tumor, poses a significant threat to public health due to its high morbidity and mortality rates. 1 Glioblastoma, the most common and invasive glioma ...
ascopubs.org

BTLA transcriptomic expression correlates with high levels of PD-1, PD-L2, and CTLA-4 checkpoints and with its ligand, HVEM, across diverse solid cancers.

PD-L1 expression in Chinese patients with solid tumor and its correlation with gene alternations. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not include a ...