This Research Topic is one volume within the series "The Future of Checkpoint Immunotherapy: New Roads Ahead". Please see the ...

Despite the transformative effect of immune checkpoint inhibitors, fewer than 20% of cancer patients achieve durable responses. One mechanism of cancer evasion involves glyco-immune checkpoints, in ...

Immune system activation and activity is regulated through stimulatory or inhibitory ligand-receptor interactions collectively termed immune checkpoints. 1 Stimulatory interactions give the immune ...

A color-enhanced microscope image showing an exosome (in blue) with PD-1 proteins on its surface (in brown). The black arrow points to the ring of PD-1. Immune checkpoint molecules play a crucial role ...

A pan-cancer analysis of 2,930 patients across 11 tumor types found that ALK mutation was associated with significantly ...

Please provide your email address to receive an email when new articles are posted on . Glucocorticoids remain the primary option for immune-related adverse events of checkpoint inhibitor therapy in ...

Immune checkpoint inhibitors are well known as a form of cancer treatment. Researchers at UZH have now identified a new, important function of these inhibitors: promotion of tissue healing. This ...

A recent study found that monthly prices of checkpoint inhibitors decreased only slightly from 2015 to 2024, with declines in annual average sales prices ranging from 0.21% to 4.85%. "Prices of ...