Microglia, the immune cells that protect the brain, are thought to maintain a healthy brain environment by removing unwanted substances through dynamic remodeling of the actin cytoskeleton, the cell's ...

We demonstrated for the first time that Hv1 is present and functional on endosomes. Additionally, Hv1 controlled actin cytoskeleton function via a protein called CapZ. The actin cytoskeleton was also ...

In the 1950s, advances in microscopy techniques allowed scientists to visualize synaptic communication between two brain cells for the first time. 1,2 However, many details beyond the general synapse ...

A recent study published in Nature Chemistry introduces an artificial cytoskeleton designed to provide mechanical support and regulate membrane dynamics in synthetic cell platforms. This system ...

It’s a scientist’s dream to observe proteins in motion: an enzyme wrapping snuggly around its substrate, or a motor protein skipping along the cytoskeleton. But tools to visualize these subtle ...

The Fowler laboratory studies cellular architecture: how cells spatially organize themselves and their interior compartments to achieve intricate geometries, mechanical strength, and physiological ...