A study in Nature Structural & Molecular Biology, led by researchers at The Wistar Institute, depicts the structure and the means of action of a protein complex called NatA. Their findings, they ...

For the first time, the structure of a DNA enzyme complex implicated in infertility and cancer has been obtained using cryo-electron microscopy (cryo-EM). A collaboration of researchers, led by ...

University of Cincinnati Cancer Center researchers looked billions of years into the past to learn more about the potential future of precision medicine. Led by first author Bibek R. Karki and senior ...

Researchers at the University of Basel have repurposed a natural enzyme so that it catalyzes a highly challenging chemical reaction. Their approach opens new possibilities for synthesizing complex ...

Figure 1: Enzyme complex showing nocardicin G (dark blue) positioned next to the 3-ACP group (green) in the enzyme active site. Reprinted with permission from Ref 1 ...

Directed evolution has enabled a high-performance biocatalyst to streamline synthesis of the HIV prevention drug lenacapavir ...

An analysis of an unusual enzyme could result in a new generation of antimicrobial medicines to counter antibiotic resistance. Key details in the enzyme-driven biosynthesis of a natural molecule with ...