For the first time, the structure of a DNA enzyme complex implicated in infertility and cancer has been obtained using cryo-electron microscopy (cryo-EM). A collaboration of researchers, led by ...

University of Cincinnati Cancer Center researchers looked billions of years into the past to learn more about the potential future of precision medicine. Led by first author Bibek R. Karki and senior ...

In a new study, scientists analyzed one such strategy used by the bacterium Escherichia coli. One of the enzymes in the ...

Researchers at the University of Basel have repurposed a natural enzyme so that it catalyzes a highly challenging chemical reaction. Their approach opens new possibilities for synthesizing complex ...

An analysis of an unusual enzyme could result in a new generation of antimicrobial medicines to counter antibiotic resistance. Key details in the enzyme-driven biosynthesis of a natural molecule with ...

Directed evolution has enabled a high-performance biocatalyst to streamline synthesis of the HIV prevention drug lenacapavir ...

Serious fungal infections are on the rise, and many hospital-acquired cases are becoming harder to treat as fungi become ...

A massive transmembrane complex, γ-secretase churns out the infamous peptides that can start a person on the path in Alzheimer’s disease. Aβ is produced when the secretase shaves three residues at a ...