Fibroblasts, cells that repair heart damage, might cause a cycle of stiffening and scarring in certain heart conditions. Dilated cardiomyopathy, a leading cause of heart failure, has been seen as ...

The researchers' success in direct reprogramming of mouse fibroblasts into alveolar epithelial-like cells may lead to new treatments for serious lung diseases. Researchers in Japan have successfully ...

Introduction Idiopathic pulmonary fibrosis (IPF) is a disease of high morbidity and mortality. We previously identified a novel subset of pathological fibroblasts, characterised by CTHRC1 expression, ...

Age-related changes in the fibroblasts, cells that create the skin's structure, contribute to the development of aggressive, treatment-resistant melanoma in males, according to research in mice by the ...

Jen Davis (left) and Bella Reichardt (right) conducting research in a lab for genetic engineering of heart fibroblasts.at the UW Medicine Institute for Stem Cell and Regeneration Medicine. Fibroblasts ...

Keloids are raised, overgrown scars that can develop after skin injuries or surgery, often extending beyond the original wound boundaries. For many people, keloids are more than just a cosmetic ...