For decades, geneticists have known that most common illnesses are not caused by a single rogue gene but by intricate constellations of DNA variants acting together in specific cells. Now a new ...
The protein-coding fraction of our genome is like the cast of a Broadway production. Their performance is critical to the success of Biology: The Musical, but a much larger production crew helps ...
A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, from mouse embryos to the roundworm C. elegans to 31 human tissues. These ...
Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health traits. By probing regions of DNA previously linked to disease, the work has ...
More than 1,000 genes may serve as possible treatment targets for individuals with kidney disease, according to a new study, published in Science, by researchers at the Perelman School of Medicine at ...
The authors of the study pictured in the facilities housing MareNostrum5, the supercomputer which was critical for processing the vast amounts of data generated by the study. Human gene maps contain ...
When someone is diagnosed with depression and anxiety, it rarely surprises their clinician. When someone with schizophrenia has mood symptoms, it rarely surprises their family. Comorbidity has always ...
Human gene maps contain major blind spots because they were built largely from the DNA sequences of people with European ancestry, according to a study published in Nature Communications. Researchers ...
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