ascopubs.org

Pharmacokinetics (PK) of the liposomal encapsulated fraction as well as released doxorubicin after intravenous infusion of liposomal doxorubicin

Celecoxib in combination with irinotecan (CPT-11), 5-fluorouracil and leucovorin in patients with advanced cancer: A phase I, pharmacokinetic study No significant financial relationships to disclose.
ascopubs.org

Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation.

Reliability and validity of the Functional Assessment of Cancer Therapy-Breast quality-of-life instrument. A phase II study of liposomal doxorubicin was conducted in patients with ovarian cancer who ...
News Medical

Characterization of Liposome Size and Encapsulation using FFF-MALS-QELS

Liposomes are synthetic vesicles composed of a lipid bilayer surrounding an aqueous core in which drugs can be contained. These vesicles therefore provide a valuable mechanism for drug delivery in the ...
Nature

Targeted radiosensitisation by pegylated liposome-encapsulated 3′, 5′-O-dipalmitoyl 5-iodo-2′-deoxyuridine in a head and neck cancer xenograft model

5-Iodo-2′-deoxyuridine (IUdR) is an effective radiosensitiser but its clinical development has been limited by toxicity. Prolonged intravenous infusions of IUdR are necessary for optimal tumour uptake ...
FiercePharma

Insys Therapeutics Receives FDA Orphan Drug Designation for Its Liposomal Encapsulated Paclitaxel for the Treatment of Ovarian Cancer

Insys Therapeutics, Inc. (NASDAQ: INSY), a specialty pharmaceutical company that is developing and commercializing innovative drugs and novel drug delivery systems, today announced that the U.S. Food ...
News Medical

Liposome Uses

Liposomes have useful properties that promote them for the use as a drug delivery system, particularly in the targeted administration for potentially toxic drugs with a narrow therapeutic index.
FierceBiotech

Insys Therapeutics Receives FDA Orphan Drug Designation for Its Liposomal Encapsulated Paclitaxel for the Treatment of Ovarian Cancer

PHOENIX, AZ, Jan 26, 2015 (Marketwired via COMTEX) -- Insys Therapeutics, Inc. INSY, +0.10% a specialty pharmaceutical company that is developing and commercializing innovative drugs and novel drug ...