A cellular-resolution map of prenatal brain development in Down syndrome reveals disrupted neuron production timing and altered cell types.

UCLA researchers created a single-cell map of the developing human neocortex in Down syndrome during a critical window of ...

Scientists mapped human brain development in Down syndrome at a cellular level, discovering that stem cells "rush" to become ...

In a bid to better understand, and potentially treat, a host of conditions that affect early cognition, neurodevelopment, and the brain later in life, investigators at Johns Hopkins Medicine and ...

The image shows how different elements of the genome are used during the birth of neurons in the mouse (left), monkey (center) and human (right) brain. Each tiny dot is a single cell in the developing ...

UCLA scientists have produced one of the first high-resolution molecular maps showing how Down syndrome disrupts human brain development before birth. The study analyzed over 100,000 nuclei from ...

The human brain's advanced cognitive capabilities are often attributed to our recently evolved neocortex. Comparison of human and rodent brains shows that the human cortex is thicker, contains more ...

Background: Neurons have dominated neuroscience research for decades, but a growing body of evidence suggests that a group of non-neuronal brain cells called glia may play an equal or greater role in ...

Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human ...