In about one out of every 1,000 pregnancies, the neural tube, a key nervous system structure, fails to close properly.

The enteric nervous system (ENS) is a sophisticated, autonomous network of neurons and glia embedded within the gastrointestinal tract, critical for regulating motility, secretion, and blood flow. The ...

How does the neural tube close? A new study uses physics-based modeling to reveal the actin "purse-string" mechanism and cellular coordination that prevents spina bifida.

When do peripheral nerves develop? Researchers used "mosaic barcodes" to prove that neural crest cells commit to their ...

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular "bridge" ...

Millions of neurons branch throughout our bodies, keeping them in close communication with our brains. This peripheral ...

The Wistar Institute's Alessandro Gardini, Ph.D., and lab have shed new light on how certain biological processes determine ...

Researchers have developed a method that shows how the nervous system and sensory organs are formed in an embryo. By labeling stem cells with a genetic 'barcode', they have been able to follow the ...

Scientists studying human neural organoids could only record and stimulate activity from limited regions because conventional flat electronics do not conform well to the tissues’ three-dimensional, ...

In 2020, researchers engineered living, programmable organisms from Xenopus laevis, calling them xenobots, which could self-assemble and even reproduce. Building on this work, scientists later ...

The Blood-Brain Barrier (BBB) is a highly selective interface that protects the brain by regulating the entry of nutrients, signaling molecules, and ...