How a key regulatory protein guides cartilage formation during embryonic development

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development ...
The Scientist

Developmental Biology

S. Piccolo, Y. Sasai, B. Lu, E.M. De Robertis, "Dorsoventral patterning in Xenopus: Inhibition of ventral signals by direct binding of chordin to BMP-4," Cell, 86:589-98, 1996. (Cited in more than 170 ...
EurekAlert!

Chimpanzee stem cells offer new insights into early embryonic development

Understanding how cells differentiate during early embryonic development is crucial for advancing regenerative medicine and developmental biology. Pluripotent stem cells (PSCs) have been invaluable ...
BioTechniques

Communication is key: unknown early embryonic signaling revealed by new model

New stem cell-based embryo model reveals previously unknown communication between early tissues that become the spine and muscles in the central part of the body. From the moment an embryo starts to ...
The Conversation

Stem cells sound magical, but they’re not all created equal. Here’s what you need to know

Most people have heard of stem cells. They are often described as “miracle” cells –ones that can grow into any other type of cell in our bodies, promising revolutionary medical treatments. However, ...