Pyrosequencing technique is based on sequencing-by-synthesis principle. The method is based on the sequencing of single stranded DNA and now-a-days sequencing of double stranded DNA is also possible.

Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter. Pal Nyren’s Eureka moment came in 1986 when he was cycling home from Cambridge university. “It is often when ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...