Objectives Owing to the underrepresentation of early-stage disease in randomised trials and inconsistent clinical evidence, ...

Background Atrial fibrillation (AF) is a common cardiac arrhythmia associated with an increased risk of stroke, heart failure ...

Here we review target trial emulation to supplement evidence from randomized trials and inform regulatory and clinical decision making in oncology. Understanding the strengths and limitations of the ...

Breast cancer survivors who maintain an exercise routine suited to their personal needs may improve their long-term survival, a new study suggests. The study, designed as a so-called target trial ...

Using statins for primary prevention is safe and beneficial in adults with type 2 diabetes irrespective of their estimated 10-year risk of cardiovascular disease at baseline, a target trial emulation ...

Researchers conducted a retrospective cohort study comparing the effectiveness and safety of abatacept vs rituximab for RA-ILD using an emulated target trial design, with data obtained from the ...

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