ascopubs.org

Disparities in Cancer Genetic Testing and Variants of Uncertain Significance in the Hispanic Population of South Texas

Racial and ethnic disparities have included a lack of access to both genetic testing and research, resulting in poor understanding of the genomic architecture in under-represented populations. The ...
ascopubs.org

Genome Sequencing of Undiagnosed European Patients Suspected of Hereditary Cancer: Diagnostic Yield and Identification of Candidate Causative Variants

Increasing Use of Germline Genetic Testing in Pancreatic Ductal Adenocarcinoma and Relationship to Clinical Outcome: A Single-Institution Study Hereditary cancers represent 5%-10% of all cancers, ...
The American Journal of Managed Care

Genetic Insights Shape Personalized Breast Cancer Management, Yet Variant Classification Uncertainty Persists

Genetic risk models, including PREMMplus and BOADICEA/CanRisk, refine breast cancer risk assessment by incorporating genetic status and polygenic risk scores. Challenges in classifying gene variants, ...

Cancer diagnosis? Genetic testing can help inform next steps

After a cancer diagnosis, patients often have many questions, not only about their treatment but also about what the ...
STAT

Can variant interpretation at scale unlock faster answers for rare disease patients?

For patients facing a rare disease, a genetic test isn’t the end of their story; it’s often just the beginning. A test result may point to a diagnosis, or it may reveal a genetic variant that we have ...