A team at Huntsman Cancer Institute at the University of Utah (the U) has uncovered a previously unrecognized molecular ...

As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune ...

Macrophages use cell‑volume changes to sense danger, reprogram gene expression, and heighten inflammatory and antiviral ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

(MEMPHIS, Tenn. – November 6, 2025) The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s “tail” called phosphorylation patterns.

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...