A single gene switch falters in heart failure—and CRISPR can revive it

In heart failure, the heart can no longer supply the body with enough blood. The condition often develops over many years, ...

How the microprotein BRICK1 repairs and protects the heart after a heart attack

Every year, more than 200,000 people in Germany suffer a heart attack. This is caused by blocked coronary arteries. As a ...
BioWorld

Human iPSCs restore muscle, function in monkeys with heart failure

Japanese researchers have transplanted human induced pluripotent stem cells (iPSCs) in a primate model of myocardial infarction and were able to restore heart muscle and function in monkeys. Developed ...
Science Daily

Using stem cell-derived heart muscle cells to advance heart regenerative therapy

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is ...
The American Journal of Managed Care

Strength Plus Aerobic Training Outperforms Aerobic Alone in HF

A new systematic review and meta-analysis appearing in the Journal of Sport and Health Science suggests that combining strength and aerobic exercise may offer greater improvements ...
GEN

Gene Therapy Reverses Effects of Heart Failure and Restores Heart Function in Minipigs

Researchers at the Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, and the University of Utah School of Medicine, have demonstrated that a gene therapy can ...