Diseases like cancer or neurodegeneration are known to arise from genetic misfires. But treating such complex conditions hasn ...

A new study published in Genome Research presents an interpretable artificial intelligence framework that improves both the accuracy and transparency of genomic prediction, a key challenge in fields ...

A new study suggests that the long-standing Mendelian view of genetics has some blind spots.

Researchers have uncovered the origins and genetic diversity of the Fulani, one of Africa's largest pastoral populations. The study reveals a complex genetic ancestry with influences from both North ...

Primary angle-closure glaucoma is a leading cause of blindness. Here, the authors identify rare deleterious variants in UBOX5 as risk factors and implicate BIP ubiquitination as a potential disease ...

A collaboration including Rice University, Baylor College of Medicine and Texas Children’s Hospital’s Jan and Dan Duncan Neurological Research Institute (NRI) has produced a breakthrough in how to ...

Structural variants (SVs) are alterations in the DNA sequence that involve large-scale changes, typically longer than 50 base pairs. Advances in long-read sequencing have significantly increased ...

Improving the genetic circuits in eukaryotic protein production systems—like human cell lines or Chinese hamster ovaries—has the potential to enhance their value so they may offer not only their own ...

A large-scale genetic analysis of East Asian individuals led by Fuu-Jen Tsai of the China Medical University Hospital, finds that people with greater height face a higher risk of endometriosis and ...