This double-blind trial enrolled adults with HIV-associated cryptococcal meningitis in Vietnam, Thailand, Indonesia, Laos, Uganda, and Malawi. All patients received combination antifungal therapy of ...

Dar es Salaam / Lilongwe / Geneva — 15 April 2025 — A new, easier-to-administer and patient-friendly sustained-release formulation of flucytosine, a medicine used to treat cryptococcal meningitis, has ...

After entering the host, the leading cause of fungal meningitis, Cryptococcus neoformans, rapidly adapts by shrinking in size and acquiring other characteristics that allow it to better infect the ...

Prefer Newsweek on Google to see more of our trusted coverage when you search. A fungus that can change its shape to fit into your brain has been discovered by scientists. Cryptococcus neoformans (C.

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Cryptococcal meningitis is a major complication of HIV infection. In this phase 3, randomized, controlled trial in sub-Saharan Africa, a single dose of liposomal amphotericin B induction therapy ...

There is hope in the fight against cryptococcal meningitis, the second leading cause of death in patients with advanced HIV (previously called AIDS), as scientists work around the clock to release new ...

C. neoformans is a fungal pathogen that causes meningitis, which causes approximately 180,000 deaths annually worldwide. Currently, AmB is the only fungicidal drug available to treat fungal meningitis ...

In a recent study published in Nature Microbiology, researchers examined metabolite-drug-fungal interactions in the fungal meningitis pathogen Cryptococcus neoformans. Antibiotic resistance refers to ...

The encapsulated fungus Cryptococcus neoformans is the most common cause of fungal meningitis, with the highest rate of cryptococcosis found in AIDS patients. Despite antifungal treatment, ...

A ground-breaking UK study has demonstrated how Cryptococcus neoformans helps meningitis infection develop by blocking and bursting blood vessels, paving the way for new treatments in the future. In ...

Researchers at the University of Utah (U of U) Health report that a fungus that is a common cause of fungal meningitis undergoes a transformation once it enters the body, allowing it to infect the ...