A study shows epigenetic proteins regulate genes through diverse dynamic patterns, not simple on-off control, with each ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a ...

This important study advances a new computational approach to measure and visualize gene expression specificity across different tissues and cell types. The framework is potentially helpful for ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

One approved drug for spinal muscular atrophy already takes this approach to restore proteins that are being shut off. Another approach could be to increase the NMD process to decrease expression, for ...

A new analysis of individual brain cells across several human brain regions reveals subtle but widespread differences in gene activity between male and female brains. This may help explain why some ...

Single-cell analyses revealed differential expression of thousands of genes in the male and female brain, which may shape sex ...