Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

In a study published in Nature Human Behaviour on Oct. 9, researchers led by Profs. TU Yiheng and HU Li from the Institute of Psychology of the Chinese Academy of Sciences have uncovered a neural ...

A breakthrough discovery reveals how the SLC45A4 gene fine-tunes polyamine transport in sensory neurons, reshaping our understanding of pain and opening new paths for targeted therapies. Study: ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...

Nearly everyone is familiar with the feeling of accidentally touching a hot vessel or holding onto something freezing for too long. Normally, pain serves to protect from potential harm, but when the ...

Chronic pain is no joke. It can upend your life, steal away your ability to live in the moment and force you to find gumption within yourself you didn’t know existed. It’s something that an estimated ...

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...