The citric acid cycle, also called the TCA or Krebs cycle, is a core metabolic pathway and a high-yield MCAT topic. It converts acetyl-CoA into ATP, NADH, and FADH2 through a sequence of enzyme-driven ...

Endogenous pyruvate is an end-product in glycolysis and a key molecule for ATP production under aerobic and anaerobic conditions, whereas exogenous pyruvate is transferred to cells via monocarboxylate ...

Two simple molecules can react to form most of the intermediates in an analog of the modern-day Krebs cycle, without the need for enzymes or metals, according to a new study (Nat. Chem. 2020, DOI: ...