RNA molecules exhibit an astonishing diversity in structure, which is integral to their myriad cellular functions ranging from gene regulation to catalysis. Advances in experimental techniques and ...
Artificial intelligence (AI) and machine learning are increasingly being applied in the field of RNA biology. These methods are used to predict RNA structures, interactions with proteins and small ...
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Study: RNA drugs work best when they reshape RNA, not just bind to it
Researchers led by Davide Incarnato at the University of Groningen have demonstrated that the FDA-approved cancer drug ...
Researchers show small molecules that alter RNA structure have greater functional impact than those that only bind, offering ...
Studying a trio of non-coding RNA molecules produced abundantly in bacterial cells, a SLAC/Stanford-led research team discovered extravagant, multistrand complexes made entirely of RNA—structures they ...
RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...
Atomic-resolution structure of a ribozyme yields insights into RNA catalysis and the origins of life
Which came first, nucleic acids or proteins? This question is molecular biology’s version of the “chicken-or-the-egg” riddle. Genes made of nucleic acids (DNA or RNA) contain the instructions for ...
Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...
Rutgers University–Newark researchers have developed a first-of-its-kind RNA nanotechnology. The development self-assembles inside living human cells and can be programmed to halt the growth of ...
Researchers test state-of-the-art models on diverse RNA structures, opening doors for RNA-based therapies and drug design Ribonucleic acid (RNA) is one of life’s most versatile molecules, with roles ...
Platform combines proprietary AI sequence optimization, novel genetic parts, and lab validation in application-relevant cell models to improve expression and half-life, delivering top candidates in ...
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