Timelapse of a gene-edited medaka fish embryo undergoing mitosis. The mitotic spindle – the green strands in the middle of the cells – can be seen aligning and segregating duplicated chromosomes, ...
Mitotic segregation of chromosomes depends on correct assembly of the bipolar spindle and mitosis is delayed by the spindle assembly checkpoint (SAC). In the July 19 Nature, Gachet et al., at the ...
Intratumor heterogeneity of DNA copy number aberrations in gastric and oesophageal adenocarcinomas. Lapatinib combined with ECF/x as first-line metastatic gastric cancer (GC) according to HER2 and ...
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An open-label, phase II study of tipifarnib for the treatment of HRAS mutant solid tumors, including squamous cell carcinomas of the head and neck. Background: TTK (MPS1), a dual-specificity ...
New research sheds light on embryonic mitosis, thanks to a combination of novel imaging techniques, CRISPR/Cas9 genome editing technology, a modern protein-knockdown system, and medaka, or Japanese ...
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