eLife

Serotonergic modulation of motor subspace dynamics drives a sleep-independent quiescent state

The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...
eLife

Molidustat Targets a Synthetic Lethal Vulnerability in APC-Mutant Colorectal Cancer through GSTP1 and PHD2 Co-Inhibition

This important paper substantially advances our understanding of how Molidustat may work, beyond its canonical role, by identifying its therapeutic targets in cancer. This study presents a compelling ...
AHA/ASA Journals

Defective Trophoblast Differentiation, Endothelial Dysfunction, and Immune Dysregulation in Preeclampsia Coalesce on a Placental VGLL3-Centered Gene …

BACKGROUND: Preeclampsia affects approximately 1 in 10 pregnancies, leading to severe complications and long-term health ...
BMJ Open

Co-exploring how environments shape brain health through a planetary health lens: a photovoice study in Auckland, Aotearoa New Zealand

Objectives Dementia prevention and climate action share a common imperative: safeguarding future generations’ health. Despite ...
Bangkok Post

Guru's Weekly Buzz: April 10-16

Silom adds a new dimension to the 2026 festivities with "CP Splash To Space" at CP Tower Silom from April 12–14. The space-themed festival is inspired by CPF's "Thai Chicken Mission To Space" ...
The Del Norte Triplicate

Bury face into pure gold.

Crowder near the bomb. Riding mower or garden issue? Quality and real milk start? China seemingly headed for crash? Downtown should be entertaining. Meaning brand new. My ending place. Crank on that ...